Non-communicable diseases (diabetes, renal disease, cardiovascular disease and cancer) consumed most of medical expenditure but caused most death tolls in Taiwan. The prevention and management of non-communicable disease had expended many emerging issues that need further research. Therefore, our study directions focus on (1) identifying the determinants and predictors of chronic diseases, including cancer, cardiovascular disease, renal disease and metabolic disorders, (2) Detecting and evaluating short-term or long-term medication-related adverse events for chronic diseases, (3) identifying the potential modifiable risk factors and protective factors of chronic disease. Our study teams currently aim to:

• Investigate the relationship between carotid hemodynamic factors and cerebrovascular disease, included stroke and cognitive function impairment;
• Evaluate the relationship between atherosclerosis and arteriosclerosis and cardiovascular mortality;
• Evaluate the association between effects of drug use and cardiovascular disease events in diabetic patients, chronic kidney disease patients, or other high risk populations;
• Identify and evaluate the relationship between dietary factors and cognitive function impairment;
• Conduct epidemiological studies on diabetes, diabetic nephropathy, and chronic kidney disease;
• Assess the impact of pre-existing medical conditions/comorbidities on cancer prognosis.